A Novel Viral Assembly Inhibitor Blocks SARS-CoV-2 Replication in Airway Epithelial Cells

The ongoing evolution of SARS-CoV-2 to evade vaccines and therapeutics underlines the need for novel therapies with high genetic barriers to resistance. The small molecule PAV-104, identified through a cell-free protein synthesis and assembly screen, was recently shown to target host protein assembl...

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Detalles Bibliográficos
Autores principales: Pillai, Satish, Du, Li, Deiter, Fred, Bouzidi, Mohamed, Billaud, Jean-Noel, Graham, Simmons, Prerna, Dabral, Selvarajah, Suganya, Lingappa, Anuradha, Michon, Maya, Yu, Shao, Paulvannan, Kumar, Lingappa, Vishwanath, Boushey, Homer, Greenland, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246244/
https://www.ncbi.nlm.nih.gov/pubmed/37292622
http://dx.doi.org/10.21203/rs.3.rs-2887435/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246244/
https://www.ncbi.nlm.nih.gov/pubmed/37292622
http://dx.doi.org/10.21203/rs.3.rs-2887435/v1

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