NMNAT2 supports vesicular glycolysis via NAD homeostasis to fuel fast axonal transport

BACKGROUND: Bioenergetic maladaptations and axonopathy are often found in the early stages of neurodegeneration. Nicotinamide adenine dinucleotide (NAD), an essential cofactor for energy metabolism, is mainly synthesized by Nicotinamide mononucleotide adenylyl transferase 2 (NMNAT2) in CNS neurons....

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Detalles Bibliográficos
Autores principales: Yang, Sen, Niou, Zhen-Xian, Enriquez, Andrea, LaMar, Jacob, Huang, Jui-Yen, Ling, Karen, Jafar-Nejad, Paymaan, Gilley, Jonathan, Coleman, Michael P., Tennessen, Jason M., Rangaraju, Vidhya, Lu, Hui-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246254/
https://www.ncbi.nlm.nih.gov/pubmed/37292715
http://dx.doi.org/10.21203/rs.3.rs-2859584/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246254/
https://www.ncbi.nlm.nih.gov/pubmed/37292715
http://dx.doi.org/10.21203/rs.3.rs-2859584/v1

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