Up-regulation of Myocardial Klotho Expression to Promote Cardiac Functional Recovery in Old Mice following Endotoxemia

OBJECTIVE: Endotoxemic cardiac dysfunction contributes to greater morbidity and mortality in elderly patients with sepsis. This study tested the hypothesis that Klotho insufficiency in aging heart exaggerates and prolongs myocardial inflammation to hinder cardiac function recovery following endotoxe...

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Detalles Bibliográficos
Autores principales: Li, Xueting, Zhai, Yufeng, Yao, Qingzhou, The, Erlinda, Ao, Lihua, Fullerton, David A., Yu, Kai-Jiang, Meng, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246261/
https://www.ncbi.nlm.nih.gov/pubmed/37292905
http://dx.doi.org/10.21203/rs.3.rs-2949854/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246261/
https://www.ncbi.nlm.nih.gov/pubmed/37292905
http://dx.doi.org/10.21203/rs.3.rs-2949854/v1

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