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Up-regulation of Myocardial Klotho Expression to Promote Cardiac Functional Recovery in Old Mice following Endotoxemia
OBJECTIVE: Endotoxemic cardiac dysfunction contributes to greater morbidity and mortality in elderly patients with sepsis. This study tested the hypothesis that Klotho insufficiency in aging heart exaggerates and prolongs myocardial inflammation to hinder cardiac function recovery following endotoxe...
Autores principales: | Li, Xueting, Zhai, Yufeng, Yao, Qingzhou, The, Erlinda, Ao, Lihua, Fullerton, David A., Yu, Kai-Jiang, Meng, Xianzhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246261/ https://www.ncbi.nlm.nih.gov/pubmed/37292905 http://dx.doi.org/10.21203/rs.3.rs-2949854/v1 |
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