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Pan-cancer transcriptomic analysis of CNS tumor stroma identifies a population of perivascular fibroblasts that predict poor immunotherapy response in glioblastoma patients

Excessive deposition of extracellular matrix (ECM) is a hallmark of solid tumors; however, it remains poorly understood which cellular and molecular components contribute to the formation of ECM stroma in central nervous system (CNS) tumors. Here, we undertook a pan-CNS analysis of retrospective gen...

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Detalles Bibliográficos
Autores principales: Zarodniuk, Maksym, Steele, Alexander, Lu, Xin, Li, Jun, Datta, Meenal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246264/
https://www.ncbi.nlm.nih.gov/pubmed/37292803
http://dx.doi.org/10.21203/rs.3.rs-2931886/v1