Lupus autoantibodies initiate a maladaptive equilibrium sustained by HMGB1:RAGE signaling and reversed by LAIR-1:C1q signaling

Cognitive impairment is a frequent manifestation of neuropsychiatric systemic lupus erythematosus (NPSLE), present in up to 80% of patients and leading to a diminished quality of life. We have developed a model of lupus-like cognitive impairment which is initiated when anti-DNA, anti-N-methyl D-aspa...

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Detalles Bibliográficos
Autores principales: Carroll, Kaitlin R., Mizrachi, Mark, Simmons, Sean, Toz, Bahtiyar, Wingard, Jeffrey, Tehrani, Nazila, Zarfeshani, Aida, Kello, Nina, Kowal, Czeslawa, Levin, Joshua Z., Volpe, Bruce T., Diamond, Betty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246276/
https://www.ncbi.nlm.nih.gov/pubmed/37292843
http://dx.doi.org/10.21203/rs.3.rs-2870168/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246276/
https://www.ncbi.nlm.nih.gov/pubmed/37292843
http://dx.doi.org/10.21203/rs.3.rs-2870168/v1

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