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Parasite proteostasis and artemisinin resistance

The continued emergence and spread of resistance to artemisinins, the cornerstone of first line antimalarials, threatens significant gains made toward malaria elimination. Mutations in Kelch13 have been proposed to mediate artemisinin resistance by either reducing artemisinin activation via reduced...

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Detalles Bibliográficos
Autores principales: Rosenthal, Melissa, Ng, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246279/
https://www.ncbi.nlm.nih.gov/pubmed/37292709
http://dx.doi.org/10.21203/rs.3.rs-2926003/v1