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Rescuing biologically relevant consensus regions across replicated samples

BACKGROUND: Protein-DNA binding sites of ChIP-seq experiments are identified where the binding affinity is significant based on a given threshold. The choice of the threshold is a trade-off between conservative region identification and discarding weak, but true binding sites. RESULTS: We rescue wea...

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Detalles Bibliográficos
Autores principales: Jalili, Vahid, Cremona, Marzia A., Palluzzi, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246347/
https://www.ncbi.nlm.nih.gov/pubmed/37286963
http://dx.doi.org/10.1186/s12859-023-05340-x