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Rescuing biologically relevant consensus regions across replicated samples
BACKGROUND: Protein-DNA binding sites of ChIP-seq experiments are identified where the binding affinity is significant based on a given threshold. The choice of the threshold is a trade-off between conservative region identification and discarding weak, but true binding sites. RESULTS: We rescue wea...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246347/ https://www.ncbi.nlm.nih.gov/pubmed/37286963 http://dx.doi.org/10.1186/s12859-023-05340-x |