Lymphocyte activation gene 3 is increased and affects cytokine production in rheumatoid arthritis

BACKGROUND: Lymphocyte activation gene-3 (LAG-3) inhibits T cell activation and interferes with the immune response by binding to MHC-II. As antigen presentation is central in rheumatoid arthritis (RA) pathogenesis, we studied aspects of LAG-3 as a serological marker and mediator in the pathogenesis...

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Detalles Bibliográficos
Autores principales: Pedersen, Janni Maria, Hansen, Aida Solhøj, Skejø, Cæcilie, Juul-Madsen, Kristian, Junker, Peter, Hørslev-Petersen, Kim, Hetland, Merete Lund, Stengaard-Pedersen, Kristian, Østergaard, Mikkel, Møller, Bjarne Kuno, Dreyer, Lene, Hauge, Ellen-Margrethe, Hvid, Malene, Greisen, Stinne, Deleuran, Bent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246404/
https://www.ncbi.nlm.nih.gov/pubmed/37287025
http://dx.doi.org/10.1186/s13075-023-03073-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246404/
https://www.ncbi.nlm.nih.gov/pubmed/37287025
http://dx.doi.org/10.1186/s13075-023-03073-z

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