Hippocampal versus cortical deletion of cholinergic receptor muscarinic 1 in mice differentially affects post-translational modifications and supramolecular assembly of respiratory chain-associated proteins, mitochondrial ultrastructure, and respiration: implications in Alzheimer’s disease

Introduction: In a previous retrospective study using postmortem human brain tissues, we demonstrated that loss of Cholinergic Receptor Muscarinic 1 (CHRM1) in the temporal cortex of a subset of Alzheimer’s patients was associated with poor survival, whereas similar loss in the hippocampus showed no...

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Detalles Bibliográficos
Autores principales: Sabbir, Mohammad Golam, Swanson, Mamiko, Speth, Robert C., Albensi, Benedict C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246746/
https://www.ncbi.nlm.nih.gov/pubmed/37293125
http://dx.doi.org/10.3389/fcell.2023.1179252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246746/
https://www.ncbi.nlm.nih.gov/pubmed/37293125
http://dx.doi.org/10.3389/fcell.2023.1179252

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