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Sortilin Inhibition Protects Neurons From Degeneration in the Diabetic Retina

PURPOSE: To investigate the level and localization of the multifunctional receptor sortilin in the diabetic retina, as well as the effect of sortilin inhibition on retinal neurodegeneration in experimental diabetes. METHODS: The localization of sortilin and colocalization with the p75 neurotrophin r...

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Detalles Bibliográficos
Autores principales: Jakobsen, Thomas Stax, Østergaard, Jakob Appel, Kjolby, Mads, Birch, Elisa Lund, Bek, Toke, Nykjaer, Anders, Corydon, Thomas J., Askou, Anne Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246757/
https://www.ncbi.nlm.nih.gov/pubmed/37272764
http://dx.doi.org/10.1167/iovs.64.7.8