In Vitro Testing of the Virus-Like Drug Conjugate Belzupacap Sarotalocan (AU-011) on Uveal Melanoma Suggests BAP1-Related Immunostimulatory Capacity

PURPOSE: The virus-like drug conjugate belzupacap sarotalocan (AU-011), currently under clinical investigation for first-line treatment of primary uveal melanoma (UM), shows enhanced tumor specificity by targeting heparan sulfate proteoglycans (HSPG). Such a treatment may potentially lead to systemi...

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Detalles Bibliográficos
Autores principales: Ma, Sen, Huis In't Veld, Ruben V., Houy, Alexander, Stern, Marc-Henri, Rich, Cadmus, Ossendorp, Ferry A., Jager, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Anatomy and Pathology/Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246758/
https://www.ncbi.nlm.nih.gov/pubmed/37272766
http://dx.doi.org/10.1167/iovs.64.7.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246758/
https://www.ncbi.nlm.nih.gov/pubmed/37272766
http://dx.doi.org/10.1167/iovs.64.7.10

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