Pyruvate decarboxylase and thiamine biosynthetic genes are regulated differently by Pdc2 in S. cerevisiae and C. glabrata

Understanding metabolism in the pathogen Candida glabrata is key to identifying new targets for antifungals. The thiamine biosynthetic (THI) pathway is partially defective in C. glabrata, but the transcription factor CgPdc2 upregulates some thiamine biosynthetic and transport genes. One of these gen...

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Detalles Bibliográficos
Autores principales: Iosue, Christine L., Ugras, Julia M., Bajgain, Yakendra, Dottor, Cory A., Stauffer, Peyton L., Hopkins, Rachael A., Lang, Emma C., Wykoff, Dennis D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246790/
https://www.ncbi.nlm.nih.gov/pubmed/37285346
http://dx.doi.org/10.1371/journal.pone.0286744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246790/
https://www.ncbi.nlm.nih.gov/pubmed/37285346
http://dx.doi.org/10.1371/journal.pone.0286744

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