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Quantitative intravital imaging for real-time monitoring of pancreatic tumor cell hypoxia and stroma in an orthotopic mouse model

Pancreatic cancer is a lethal disease with few successful treatment options. Recent evidence demonstrates that tumor hypoxia promotes pancreatic tumor invasion, metastasis, and therapy resistance. However, little is known about the complex relationship between hypoxia and the pancreatic tumor microe...

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Detalles Bibliográficos
Autores principales: Samuel, Timothy, Rapic, Sara, O’Brien, Cristiana, Edson, Michael, Zhong, Yuan, DaCosta, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246908/
https://www.ncbi.nlm.nih.gov/pubmed/37285434
http://dx.doi.org/10.1126/sciadv.ade8672