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Quantitative intravital imaging for real-time monitoring of pancreatic tumor cell hypoxia and stroma in an orthotopic mouse model
Pancreatic cancer is a lethal disease with few successful treatment options. Recent evidence demonstrates that tumor hypoxia promotes pancreatic tumor invasion, metastasis, and therapy resistance. However, little is known about the complex relationship between hypoxia and the pancreatic tumor microe...
Autores principales: | Samuel, Timothy, Rapic, Sara, O’Brien, Cristiana, Edson, Michael, Zhong, Yuan, DaCosta, Ralph S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10246908/ https://www.ncbi.nlm.nih.gov/pubmed/37285434 http://dx.doi.org/10.1126/sciadv.ade8672 |
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