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Is iron deficiency caused by BMPR2 mutations or dysfunction in pulmonary arterial hypertension patients?

Iron deficiency is common in idiopathic and heritable pulmonary arterial hypertension patients (I/HPAH). A previous report suggested a dysregulation of the iron hormone hepcidin, which is controlled by BMP/SMAD signaling involving the bone morphogenetic protein receptor 2 (BMPR‐II). Pathogenic varia...

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Detalles Bibliográficos
Autores principales: Theobald, Vivienne, Grünig, Ekkehard, Benjamin, Nicola, Seyfarth, Hans‐Jürgen, Halank, Michael, Schneider, Marc A., Richtmann, Sarah, Kazdal, Daniel, Hinderhofer, Katrin, Xanthouli, Panagiota, Egenlauf, Benjamin, Harutyunova, Satenik, Hoeper, Marius M., Jonigk, Danny, Sparla, Richard, Muckenthaler, Martina U., Eichstaedt, Christina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247310/
https://www.ncbi.nlm.nih.gov/pubmed/37292089
http://dx.doi.org/10.1002/pul2.12242