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Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum

The endoplasmic reticulum (ER) undergoes continuous remodelling via a selective autophagy pathway, known as ER-phagy(1). ER-phagy receptors have a central role in this process(2), but the regulatory mechanism remains largely unknown. Here we report that ubiquitination of the ER-phagy receptor FAM134...

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Detalles Bibliográficos
Autores principales: González, Alexis, Covarrubias-Pinto, Adriana, Bhaskara, Ramachandra M., Glogger, Marius, Kuncha, Santosh K., Xavier, Audrey, Seemann, Eric, Misra, Mohit, Hoffmann, Marina E., Bräuning, Bastian, Balakrishnan, Ashwin, Qualmann, Britta, Dötsch, Volker, Schulman, Brenda A., Kessels, Michael M., Hübner, Christian A., Heilemann, Mike, Hummer, Gerhard, Dikić, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247366/
https://www.ncbi.nlm.nih.gov/pubmed/37225996
http://dx.doi.org/10.1038/s41586-023-06089-2