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Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy

Membrane-shaping proteins characterized by reticulon homology domains play an important part in the dynamic remodelling of the endoplasmic reticulum (ER). An example of such a protein is FAM134B, which can bind LC3 proteins and mediate the degradation of ER sheets through selective autophagy (ER-pha...

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Detalles Bibliográficos
Autores principales: Foronda, Hector, Fu, Yangxue, Covarrubias-Pinto, Adriana, Bocker, Hartmut T., González, Alexis, Seemann, Eric, Franzka, Patricia, Bock, Andrea, Bhaskara, Ramachandra M., Liebmann, Lutz, Hoffmann, Marina E., Katona, Istvan, Koch, Nicole, Weis, Joachim, Kurth, Ingo, Gleeson, Joseph G., Reggiori, Fulvio, Hummer, Gerhard, Kessels, Michael M., Qualmann, Britta, Mari, Muriel, Dikić, Ivan, Hübner, Christian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247384/
https://www.ncbi.nlm.nih.gov/pubmed/37225994
http://dx.doi.org/10.1038/s41586-023-06090-9