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AMG-510 and cisplatin combination increases antitumor effect in lung adenocarcinoma with mutation of KRAS G12C: a preclinical and translational research

BACKGROUND: The efficacy of monotherapy of AMG-510 is limited. This study explored whether the AMG-510 and cisplatin combination increases the anti-tumor effect in lung adenocarcinoma with the mutation of Kirsten rat sarcoma viral oncogene (KRAS) G12C. METHODS: Patients’ data were used to analyze th...

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Detalles Bibliográficos
Autores principales: Wu, Lei-Lei, Jiang, Wen-Mei, Liu, Zhi-Yuan, Zhang, Yi-Yi, Qian, Jia-Yi, Liu, Yu’e, Huang, Yang-Yu, Li, Kun, Li, Zhi-Xin, Ma, Guo-Wei, Xie, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247598/
https://www.ncbi.nlm.nih.gov/pubmed/37284902
http://dx.doi.org/10.1007/s12672-023-00698-z