A probiotic bi-functional peptidoglycan hydrolase sheds NOD2 ligands to regulate gut homeostasis in female mice

Secreted proteins are one of the direct molecular mechanisms by which microbiota influence the host, thus constituting a promising field for drug discovery. Here, through bioinformatics-guided screening of the secretome of clinically established probiotics from Lactobacillus, we identify an uncharac...

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Detalles Bibliográficos
Autores principales: Gao, Jie, Wang, Lei, Jiang, Jing, Xu, Qian, Zeng, Nianyi, Lu, Bingyun, Yuan, Peibo, Sun, Kai, Zhou, Hongwei, He, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247697/
https://www.ncbi.nlm.nih.gov/pubmed/37286542
http://dx.doi.org/10.1038/s41467-023-38950-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247697/
https://www.ncbi.nlm.nih.gov/pubmed/37286542
http://dx.doi.org/10.1038/s41467-023-38950-3

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