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Impaired flux of bile acids from the liver to the gut reveals microbiome-immune interactions associated with liver damage

Currently, there is evidence that alteration in the gut ecosystem contributes to the development of liver diseases, however, the complex mechanisms involved are still unclear. We induced cholestasis in mice by bile duct ligation (BDL), mirroring the phenotype of a bile duct obstruction, to understan...

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Detalles Bibliográficos
Autores principales: Leung, Howell, Xiong, Ling, Ni, Yueqiong, Busch, Anne, Bauer, Michael, Press, Adrian T., Panagiotou, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247725/
https://www.ncbi.nlm.nih.gov/pubmed/37286586
http://dx.doi.org/10.1038/s41522-023-00398-0