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Mesenchymal properties of iPSC-derived neural progenitors that generate undesired grafts after transplantation

Although neural stem/progenitor cells derived from human induced pluripotent stem cells (hiPSC-NS/PCs) are expected to be a cell source for cell-based therapy, tumorigenesis of hiPSC-NS/PCs is a potential problem for clinical applications. Therefore, to understand the mechanisms of tumorigenicity in...

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Detalles Bibliográficos
Autores principales: Isoda, Miho, Sanosaka, Tsukasa, Tomooka, Ryo, Mabuchi, Yo, Shinozaki, Munehisa, Andoh-Noda, Tomoko, Banno, Satoe, Mizota, Noriko, Yamaguchi, Ryo, Okano, Hideyuki, Kohyama, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247757/
https://www.ncbi.nlm.nih.gov/pubmed/37286713
http://dx.doi.org/10.1038/s42003-023-04995-9