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Comprehensive analysis of the coding and non-coding RNA transcriptome expression profiles of hippocampus tissue in tx-J animal model of Wilson's disease

Wilson's disease (WD) is an autosomal recessive disorder with a genetic basis. The predominant non-motor symptom of WD is cognitive dysfunction, although the specific genetic regulatory mechanism remains unclear. Tx-J mice, with an 82% sequence homology of the ATP7B gene to the human gene, are...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Xie, Daojun, Zhang, Juan, Cai, Biao, Yang, Bo, Zhou, Lei, Huang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247767/
https://www.ncbi.nlm.nih.gov/pubmed/37286730
http://dx.doi.org/10.1038/s41598-023-36503-8