Cargando…
The GET pathway is a major bottleneck for maintaining proteostasis in Saccharomyces cerevisiae
A hallmark of aging in a variety of organisms is a breakdown of proteostasis and an ensuing accumulation of protein aggregates and inclusions. However, it is not clear if the proteostasis network suffers from a uniform breakdown during aging or if some distinct components act as bottlenecks especial...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247811/ https://www.ncbi.nlm.nih.gov/pubmed/37286562 http://dx.doi.org/10.1038/s41598-023-35666-8 |