Ketone α-alkylation at the more-hindered site

Control of the regioselectivity of α-alkylation of carbonyl compounds is a longstanding topic of research in organic chemistry. By using stoichiometric bulky strong bases and carefully adjusting the reaction conditions, selective alkylation of unsymmetrical ketones at less-hindered α-sites has been...

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Detalles Bibliográficos
Autores principales: Li, Ming-Ming, Zhang, Tianze, Cheng, Lei, Xiao, Wei-Guo, Ma, Jin-Tao, Xiao, Li-Jun, Zhou, Qi-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247815/
https://www.ncbi.nlm.nih.gov/pubmed/37286579
http://dx.doi.org/10.1038/s41467-023-38741-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247815/
https://www.ncbi.nlm.nih.gov/pubmed/37286579
http://dx.doi.org/10.1038/s41467-023-38741-w

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