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Comparison of NTRK fusion detection methods in microsatellite-instability-high metastatic colorectal cancer

Tropomyosin receptor kinase (TRK) inhibitors have been approved for metastatic solid tumors harboring NTRK fusions, but the detection of NTRK fusions is challenging. International guidelines recommend pan-TRK immunohistochemistry (IHC) screening followed by next generation sequencing (NGS) in tumor...

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Detalles Bibliográficos
Autores principales: Schraa, Suzanna J., Stelloo, Ellen, Laclé, Miangela M., Swennenhuis, Joost F., Brosens, Lodewijk A. A., Fijneman, Remond J. A., Feitsma, Harma, Koopman, Miriam, de Leng, Wendy W., Vink, Geraldine R., Bol, Guus M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247849/
https://www.ncbi.nlm.nih.gov/pubmed/37067589
http://dx.doi.org/10.1007/s00428-023-03538-1