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Treatment of Homozygous Familial Hypercholesterolemia With ANGPTL3 Inhibitor, Evinacumab

Homozygous familial hypercholesterolemia (HoFH) is an ultra-rare, life-threatening, genetic condition characterized by markedly elevated levels of low-density lipoprotein cholesterol (LDL-C). Standard lipid-lowering therapies minimally reduce LDL-C in these patients, and lifelong serial apheresis is...

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Detalles Bibliográficos
Autores principales: Shamsudeen, Isabel, McCrindle, Brian W, Hegele, Robert A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247856/
https://www.ncbi.nlm.nih.gov/pubmed/37305647
http://dx.doi.org/10.1210/jcemcr/luad058