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β-Cyclodextrins as affordable antivirals to treat coronavirus infection

The SARS-CoV-2 pandemic made evident that there are only a few drugs against coronavirus. Here we aimed to identify a cost-effective antiviral with broad spectrum activity and high safety profile. Starting from a list of 116 drug candidates, we used molecular modelling tools to rank the 44 most prom...

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Detalles Bibliográficos
Autores principales: Raïch-Regué, Dalia, Tenorio, Raquel, Fernández de Castro, Isabel, Tarrés-Freixas, Ferran, Sachse, Martin, Perez-Zsolt, Daniel, Muñoz-Basagoiti, Jordana, Fernández-Sánchez, Sara Y., Gallemí, Marçal, Ortega-González, Paula, Fernández-Oliva, Alberto, Gabaldón, José A., Nuñez-Delicado, Estrella, Casas, Josefina, Roca, Núria, Cantero, Guillermo, Pérez, Mónica, Usai, Carla, Lorca-Oró, Cristina, Alert, Júlia-Vergara, Segalés, Joaquim, Carrillo, Jorge, Blanco, Julià, Clotet Sala, Bonaventura, Cerón-Carrasco, José P., Izquierdo-Useros, Nuria, Risco, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Masson SAS. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247892/
https://www.ncbi.nlm.nih.gov/pubmed/37311279
http://dx.doi.org/10.1016/j.biopha.2023.114997