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An efficient feeder-free and chemically-defined expansion strategy for highly purified natural killer cells derived from human cord blood

INTRODUCTION: Natural killer cells (NKCs) are immune cells that can attack cancer cells through the direct recognition of ligands without prior sensitization. Cord blood-derived NKCs (CBNKCs) represent a promising tool for allogenic NKC-based cancer immunotherapy. Efficient NKC expansion and decreas...

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Detalles Bibliográficos
Autores principales: Nakazawa, Tsutomu, Maeoka, Ryosuke, Morimoto, Takayuki, Matsuda, Ryosuke, Nakamura, Mitsutoshi, Nishimura, Fumihiko, Yamada, Shuichi, Nakagawa, Ichiro, Park, Young-Soo, Ito, Toshihiro, Nakase, Hiroyuki, Tsujimura, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247952/
https://www.ncbi.nlm.nih.gov/pubmed/37303464
http://dx.doi.org/10.1016/j.reth.2023.05.006