Engineering tandem CD33xCD146 CAR CIK (cytokine-induced killer) cells to target the acute myeloid leukemia niche

In acute myeloid leukemia (AML), malignant stem cells hijack the normal bone marrow niche where they are largely protected from the current therapeutic approaches. Thus, eradicating these progenitors is the ultimate challenge in the treatment of this disease. Specifically, the development of chimeri...

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Detalles Bibliográficos
Autores principales: Alberti, Gaia, Arsuffi, Corinne, Pievani, Alice, Salerno, Domenico, Mantegazza, Francesco, Dazzi, Francesco, Biondi, Andrea, Tettamanti, Sarah, Serafini, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247966/
https://www.ncbi.nlm.nih.gov/pubmed/37304257
http://dx.doi.org/10.3389/fimmu.2023.1192333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247966/
https://www.ncbi.nlm.nih.gov/pubmed/37304257
http://dx.doi.org/10.3389/fimmu.2023.1192333

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