Determination of mRNA copy number in degradable lipid nanoparticles via density contrast analytical ultracentrifugation

Lipid nanoparticles as delivery system for mRNA have recently attracted attention to a broader audience as COVID-19 mRNA vaccines. Their low immunogenicity and capability to deliver a variety of nucleic acids renders them an interesting and complementary alternative to gene therapy vectors like AAVs...

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Detalles Bibliográficos
Autores principales: Bepperling, Alexander, Richter, Gesa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248324/
https://www.ncbi.nlm.nih.gov/pubmed/37289289
http://dx.doi.org/10.1007/s00249-023-01663-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248324/
https://www.ncbi.nlm.nih.gov/pubmed/37289289
http://dx.doi.org/10.1007/s00249-023-01663-y

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