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Determination of mRNA copy number in degradable lipid nanoparticles via density contrast analytical ultracentrifugation
Lipid nanoparticles as delivery system for mRNA have recently attracted attention to a broader audience as COVID-19 mRNA vaccines. Their low immunogenicity and capability to deliver a variety of nucleic acids renders them an interesting and complementary alternative to gene therapy vectors like AAVs...
Autores principales: | Bepperling, Alexander, Richter, Gesa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248324/ https://www.ncbi.nlm.nih.gov/pubmed/37289289 http://dx.doi.org/10.1007/s00249-023-01663-y |
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