Behavioral and neuro-functional consequences of eliminating the KCNQ3 GABA binding site in mice

Voltage-gated potassium (Kv) channels formed by α subunits KCNQ2-5 are important in regulating neuronal excitability. We previously found that GABA directly binds to and activates channels containing KCNQ3, challenging the traditional understanding of inhibitory neurotransmission. To investigate the...

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Detalles Bibliográficos
Autores principales: Chen, Kiki J., Yoshimura, Ryan, Edmundo, Clarissa Adriana, Truong, Tri Minh, Civelli, Olivier, Alachkar, Amal, Abbott, Geoffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248464/
https://www.ncbi.nlm.nih.gov/pubmed/37305551
http://dx.doi.org/10.3389/fnmol.2023.1192628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248464/
https://www.ncbi.nlm.nih.gov/pubmed/37305551
http://dx.doi.org/10.3389/fnmol.2023.1192628

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