The adapter protein FADD provides an alternate pathway for entry into the cell cycle by regulating APC/C-Cdh1 E3 ubiquitin ligase activity

The E3 ubiquitin ligase APC/C-Cdh1 maintains the G0/G1 state, and its inactivation is required for cell cycle entry. We reveal a novel role for Fas-associated protein with death domain (FADD) in the cell cycle through its function as an inhibitor of APC/C-Cdh1. Using real-time, single-cell imaging o...

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Detalles Bibliográficos
Autores principales: Awadia, Sahezeel, Sitto, Merna, Ram, Sundaresh, Ji, Wenbin, Liu, Yajing, Damani, Raheema, Ray, Dipankar, Lawrence, Theodore S., Galban, Craig J., Cappell, Steven D., Rehemtulla, Alnawaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248554/
https://www.ncbi.nlm.nih.gov/pubmed/37146968
http://dx.doi.org/10.1016/j.jbc.2023.104786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248554/
https://www.ncbi.nlm.nih.gov/pubmed/37146968
http://dx.doi.org/10.1016/j.jbc.2023.104786

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