Ndel1 disfavors dynein–dynactin–adaptor complex formation in two distinct ways

Dynein is the primary minus-end-directed microtubule motor protein. To achieve activation, dynein binds to the dynactin complex and an adaptor to form the “activated dynein complex.” The protein Lis1 aids activation by binding to dynein and promoting its association with dynactin and the adaptor. Nd...

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Detalles Bibliográficos
Autores principales: Garrott, Sharon R., Gillies, John P., Siva, Aravintha, Little, Saffron R., El Jbeily, Rita, DeSantis, Morgan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248797/
https://www.ncbi.nlm.nih.gov/pubmed/37086789
http://dx.doi.org/10.1016/j.jbc.2023.104735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248797/
https://www.ncbi.nlm.nih.gov/pubmed/37086789
http://dx.doi.org/10.1016/j.jbc.2023.104735

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