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Ndel1 disfavors dynein–dynactin–adaptor complex formation in two distinct ways
Dynein is the primary minus-end-directed microtubule motor protein. To achieve activation, dynein binds to the dynactin complex and an adaptor to form the “activated dynein complex.” The protein Lis1 aids activation by binding to dynein and promoting its association with dynactin and the adaptor. Nd...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248797/ https://www.ncbi.nlm.nih.gov/pubmed/37086789 http://dx.doi.org/10.1016/j.jbc.2023.104735 |