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Fat mass and obesity-associated factor (FTO)-mediated N6-methyladenosine regulates spermatogenesis in an age-dependent manner

N6-methyladenosine (m6A) is the most prevalent reversible RNA modification in the mammalian transcriptome. It has recently been demonstrated that m6A is crucial for male germline development. Fat mass and obesity-associated factor (FTO), a known m6A demethylase, is widely expressed in human and mous...

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Detalles Bibliográficos
Autores principales: Wu, Yifei, Li, Jincheng, Li, Chenmeijie, Lu, Shuai, Wei, Xiaoyu, Li, Yang, Xia, Wenjuan, Qian, Chunfeng, Wang, Zihang, Liu, Mingxi, Gu, Yayun, Huang, Boxian, Tan, Yueqiu, Hu, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248873/
https://www.ncbi.nlm.nih.gov/pubmed/37146971
http://dx.doi.org/10.1016/j.jbc.2023.104783