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Predominantly defective CD8(+) T cell immunity to SARS-CoV-2 mRNA vaccination in lung transplant recipients

BACKGROUND: Although mRNA vaccines have overall efficacy preventing morbidity/mortality from SARS-CoV-2 infection, immunocompromised persons remain at risk. Antibodies mostly prevent early symptomatic infection, but cellular immunity, particularly the virus-specific CD8(+) T cell response, is protec...

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Detalles Bibliográficos
Autores principales: Taus, Ellie, Shino, Michael Y., Ibarrondo, F. Javier, Hausner, Mary Ann, Hofmann, Christian, Yang, Otto O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248978/
https://www.ncbi.nlm.nih.gov/pubmed/37291575
http://dx.doi.org/10.1186/s12967-023-04234-z