EETs alleviate alveolar epithelial cell senescence by inhibiting endoplasmic reticulum stress through the Trim25/Keap1/Nrf2 axis

Alveolar epithelial cell (AEC) senescence is a key driver of a variety of chronic lung diseases. It remains a challenge how to alleviate AEC senescence and mitigate disease progression. Our study identified a critical role of epoxyeicosatrienoic acids (EETs), downstream metabolites of arachidonic ac...

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Detalles Bibliográficos
Autores principales: Zhang, Chen-Yu, Zhong, Wen-Jing, Liu, Yu-Biao, Duan, Jia-Xi, Jiang, Nan, Yang, Hui-Hui, Ma, Sheng-Chao, Jin, Ling, Hong, Jie-Ru, Zhou, Yong, Guan, Cha-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249012/
https://www.ncbi.nlm.nih.gov/pubmed/37269686
http://dx.doi.org/10.1016/j.redox.2023.102765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249012/
https://www.ncbi.nlm.nih.gov/pubmed/37269686
http://dx.doi.org/10.1016/j.redox.2023.102765

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