Design, Synthesis, and Evaluation of a New Series of Hydrazones as Small-Molecule Akt Inhibitors for NSCLC Therapy

[Image: see text] In an endeavor to identify small molecules for the management of non-small-cell lung carcinoma, 10 new hydrazone derivatives (3a–j) were synthesized. MTT test was conducted to examine their cytotoxic activities against human lung adenocarcinoma (A549) and mouse embryonic fibroblast...

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Detalles Bibliográficos
Autores principales: Erdönmez, Burak, Altıntop, Mehlika Dilek, Akalın Çiftçi, Gülşen, Özdemir, Ahmet, Ece, Abdulilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249096/
https://www.ncbi.nlm.nih.gov/pubmed/37305321
http://dx.doi.org/10.1021/acsomega.3c02331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249096/
https://www.ncbi.nlm.nih.gov/pubmed/37305321
http://dx.doi.org/10.1021/acsomega.3c02331

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