Temperature-Dependent Affinity Changes in Substrate Binding Affect the Cleavage Activity of BthC2c1

BACKGROUND: The CRISPR-Cas system is an adaptive immune mechanism for bacteria and archaea to resist foreign invasion. Currently, Cas9 and Cpf1 have been widely studied and applied in gene editing. C2c1 is a newly discovered CRISPR-Cas system endonuclease. It has broad application prospects due to i...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Dan, Liu, Jieting, Liu, Yong, Qiu, Yufei, Cao, Zhiqin, Pan, Yu, Shi, Jiayi, Yuan, Xiaohuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2023
Materias:
Life Sciences, Protein and Peptide Sciences, Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249141/
https://www.ncbi.nlm.nih.gov/pubmed/36698226
http://dx.doi.org/10.2174/0929866530666230125100320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249141/
https://www.ncbi.nlm.nih.gov/pubmed/36698226
http://dx.doi.org/10.2174/0929866530666230125100320

Ejemplares similares