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tsRNA-04002 alleviates intervertebral disk degeneration by targeting PRKCA to inhibit apoptosis of nucleus pulposus cells

BACKGROUND: Intervertebral disk degeneration (IDD) is a degenerative disease that underlies various musculoskeletal and spinal disorders and is positively correlated with age. tRNA-derived small RNAs (tsRNA), as a new small noncoding RNAs, its function in IDD is unclear. Herein, our goal was to find...

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Detalles Bibliográficos
Autores principales: Pan, Jie, Liu, Zhonghan, Shen, Bin, Xu, Jin, Dai, Gonghua, Xu, Wen, Wang, Jianjie, Li, Lijun, Cheng, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249188/
https://www.ncbi.nlm.nih.gov/pubmed/37287061
http://dx.doi.org/10.1186/s13018-023-03878-3