Defective lysosomal acidification: a new prognostic marker and therapeutic target for neurodegenerative diseases

Lysosomal acidification dysfunction has been implicated as a key driving factor in the pathogenesis of neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease. Multiple genetic factors have been linked to lysosomal de-acidification through impairing the vacuolar-type ATPase...

Descripción completa

Detalles Bibliográficos
Autores principales: Lo, Chih Hung, Zeng, Jialiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249214/
https://www.ncbi.nlm.nih.gov/pubmed/37287072
http://dx.doi.org/10.1186/s40035-023-00362-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249214/
https://www.ncbi.nlm.nih.gov/pubmed/37287072
http://dx.doi.org/10.1186/s40035-023-00362-0

Ejemplares similares