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FFAR2 antagonizes TLR2- and TLR3-induced lung cancer progression via the inhibition of AMPK-TAK1 signaling axis for the activation of NF-κB

BACKGROUND: Free fatty acid receptors (FFARs) and toll-like receptors (TLRs) recognize microbial metabolites and conserved microbial products, respectively, and are functionally implicated in inflammation and cancer. However, whether the crosstalk between FFARs and TLRs affects lung cancer progressi...

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Detalles Bibliográficos
Autores principales: Kim, Mi-Jeong, Kim, Ji Young, Shin, Ji Hye, Kang, Yeeun, Lee, Ji Su, Son, Juhee, Jeong, Soo-Kyung, Kim, Daesik, Kim, Duk-Hwan, Chun, Eunyoung, Lee, Ki-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249240/
https://www.ncbi.nlm.nih.gov/pubmed/37287005
http://dx.doi.org/10.1186/s13578-023-01038-y