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TRPA1 promotes the maturation of embryonic stem cell-derived cardiomyocytes by regulating mitochondrial biogenesis and dynamics

BACKGROUND: Cardiomyocytes derived from pluripotent stem cells (PSC-CMs) have been widely accepted as a promising cell source for cardiac drug screening and heart regeneration therapies. However, unlike adult cardiomyocytes, the underdeveloped structure, the immature electrophysiological properties...

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Detalles Bibliográficos
Autores principales: Ding, Qianqian, Liu, Xianji, Qi, Yanxiang, Yao, Xiaoqiang, Tsang, Suk Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249273/
https://www.ncbi.nlm.nih.gov/pubmed/37287081
http://dx.doi.org/10.1186/s13287-023-03388-3