Influence of Mg(2+) Distribution on the Stability of Folded States of the Twister Ribozyme Revealed Using Grand Canonical Monte Carlo and Generative Deep Learning Enhanced Sampling

[Image: see text] Metal ions, particularly magnesium ions (Mg(2+)), play a role in stabilizing the tertiary structures of RNA molecules. Theoretical models and experimental techniques show that metal ions can change RNA dynamics and how it transitions through different stages of folding. However, th...

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Detalles Bibliográficos
Autores principales: Sengul, Mert Y., MacKerell, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249389/
https://www.ncbi.nlm.nih.gov/pubmed/37305323
http://dx.doi.org/10.1021/acsomega.3c00931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249389/
https://www.ncbi.nlm.nih.gov/pubmed/37305323
http://dx.doi.org/10.1021/acsomega.3c00931

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