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Influence of Mg(2+) Distribution on the Stability of Folded States of the Twister Ribozyme Revealed Using Grand Canonical Monte Carlo and Generative Deep Learning Enhanced Sampling
[Image: see text] Metal ions, particularly magnesium ions (Mg(2+)), play a role in stabilizing the tertiary structures of RNA molecules. Theoretical models and experimental techniques show that metal ions can change RNA dynamics and how it transitions through different stages of folding. However, th...
Autores principales: | Sengul, Mert Y., MacKerell, Alexander D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249389/ https://www.ncbi.nlm.nih.gov/pubmed/37305323 http://dx.doi.org/10.1021/acsomega.3c00931 |
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