Synergy effects of copper ion in doxorubicin-based chelate prodrug for cancer chemo-chemodynamic combination therapy

Doxorubicin (DOX) is a commonly studied chemotherapeutic agent for the treatment of solid tumors, but the severe side effects limit its clinical application. It is shown that DOX-metal chelate has lower in vitro cytotoxicity compared with DOX, as the anthracyclines of DOX can form coordinative inter...

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Detalles Bibliográficos
Autores principales: Zhang, Wen, Zhang, Peng, Xu, Xiaopeng, Li, Minghui, Wang, Shasha, Mu, Hongjie, Sun, Kaoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249455/
https://www.ncbi.nlm.nih.gov/pubmed/37282832
http://dx.doi.org/10.1080/10717544.2023.2219426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249455/
https://www.ncbi.nlm.nih.gov/pubmed/37282832
http://dx.doi.org/10.1080/10717544.2023.2219426

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