Meta-omics profiling of the gut-lung axis illuminates metabolic networks and host-microbial interactions associated with elevated lung elastance in a murine model of obese allergic asthma

Obesity and associated changes to the gut microbiome worsen airway inflammation and hyperresponsiveness in asthma. Obesogenic host-microbial metabolomes have altered production of metabolites that may influence lung function and inflammatory responses in asthma. To understand the interplay of the gu...

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Detalles Bibliográficos
Autores principales: Heinrich, Victoria A., Uvalle, Crystal, Manni, Michelle L., Li, Kelvin, Mullett, Steven J., Donepudi, Sri Ramya, Clader, Jason, Fitch, Adam, Ellgass, Madeline, Cechova, Veronika, Qin, Shulin, Holguin, Fernando, Freeman, Bruce A., Methé, Barbara A., Morris, Alison, Gelhaus, Stacy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249466/
https://www.ncbi.nlm.nih.gov/pubmed/37293566
http://dx.doi.org/10.3389/frmbi.2023.1153691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249466/
https://www.ncbi.nlm.nih.gov/pubmed/37293566
http://dx.doi.org/10.3389/frmbi.2023.1153691

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