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Meta-omics profiling of the gut-lung axis illuminates metabolic networks and host-microbial interactions associated with elevated lung elastance in a murine model of obese allergic asthma
Obesity and associated changes to the gut microbiome worsen airway inflammation and hyperresponsiveness in asthma. Obesogenic host-microbial metabolomes have altered production of metabolites that may influence lung function and inflammatory responses in asthma. To understand the interplay of the gu...
Autores principales: | Heinrich, Victoria A., Uvalle, Crystal, Manni, Michelle L., Li, Kelvin, Mullett, Steven J., Donepudi, Sri Ramya, Clader, Jason, Fitch, Adam, Ellgass, Madeline, Cechova, Veronika, Qin, Shulin, Holguin, Fernando, Freeman, Bruce A., Methé, Barbara A., Morris, Alison, Gelhaus, Stacy L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10249466/ https://www.ncbi.nlm.nih.gov/pubmed/37293566 http://dx.doi.org/10.3389/frmbi.2023.1153691 |
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